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1

Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia

Elgamal, Ola A., Mehmood, Abeera, Jeon, Jae Yoon, Carmichael, Bridget, Lehman, Amy, Orwick, Shelley J., Truxall, Jean, Goettl, Virginia M., Wasmuth, Ronni, Tran, Minh, Mitchell, Shaneice, Lapalombella

Journal:

Journal of Hematology & Oncology

Year:

2020

Language:

english

File:

PDF, 3.07 MB

english, 2020

2

Leukemic B Cell CTLA-4 Suppresses Costimulation of T Cells

Do, Priscilla, Beckwith, Kyle A., Cheney, Carolyn, Tran, Minh, Beaver, Larry, Griffin, Brittany G., Mo, Xiaokui, Liu, Yang, Lapalombella, Rosa, Hertlein, Erin, Muthusamy, Natarajan, Byrd, John C.

Journal:

The Journal of Immunology

Year:

2019

Language:

english

File:

PDF, 2.42 MB

english, 2019

3

Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation

Alinari, L., Mahasenan, K. V., Yan, F., Karkhanis, V., Chung, J.-H., Smith, E. M., Quinion, C., Smith, P. L., Kim, L., Patton, J. T., Lapalombella, R., Yu, B., Wu, Y., Roy, S., De Leo, A., Pileri, S.,

Journal:

Year:

2015

Language:

english

File:

PDF, 3.52 MB

english, 2015

4

Mitochondria on the move: BMSCs fuel AML energy

Lapalombella, Rosa

Journal:

Year:

2017

File:

PDF, 645 KB

2017

5

The humanized CD40 antibody SGN-40 demonstrates pre-clinical activity that is enhanced by lenalidomide in chronic lymphocytic leukaemia

Rosa Lapalombella, Aruna Gowda, Trupti Joshi, Najma Mehter, Carolyn Cheney, Amy Lehman, Ching-Shih Chen, Amy J. Johnson, Michael A. Caligiuri, Susheela Tridandapani, Natarajan Muthusamy, John C. Byrd

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 253 KB

english, 2009

6

MHC Variability in an Isolated Wolf Population in Italy

Galaverni, M., Caniglia, R., Fabbri, E., Lapalombella, S., Randi, E.

Journal:

Journal of Heredity

Year:

2013

Language:

english

File:

PDF, 9.76 MB

english, 2013

7

First evidence of hybridization between golden jackal ( Canis aureus ) and domestic dog ( Canis familiaris ) as revealed by genetic markers

Galov, Ana, Fabbri, Elena, Caniglia, Romolo, Arbanasić, Haidi, Lapalombella, Silvana, Florijančić, Tihomir, Bošković, Ivica, Galaverni, Marco, Randi, Ettore

Journal:

Royal Society Open Science

Year:

2015

Language:

english

File:

PDF, 916 KB

english, 2015

8

RECURRENT XPO1 MUTATIONS IDENTIFIED AS PREDICTIVE MARKER FOR ADVANCED CLL PROGRESSION

Walker, J. S., Hing, Z. A., Harrington, B., Oakes, C., Ozer, H. G., Lehman, A., Skinner, J., Cempre, C., Coppola, V., Byrd, J. C., Lapalombella, R.

Journal:

Year:

2019

File:

PDF, 201 KB

2019

9

The Proteasome Inhibitor Carfilzomib Functions Independently of p53 to Induce Cytotoxicity and an Atypical NF- B Response in Chronic Lymphocytic Leukemia Cells

Gupta, S. V., Hertlein, E., Lu, Y., Sass, E. J., Lapalombella, R., Chen, T. L., Davis, M. E., Woyach, J. A., Lehman, A., Jarjoura, D., Byrd, J. C., Lucas, D. M.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.25 MB

english, 2013

10

Higher Doses of Lenalidomide Are Associated With Unacceptable Toxicity Including Life-Threatening Tumor Flare in Patients With Chronic Lymphocytic Leukemia

Andritsos, L. A., Johnson, A. J., Lozanski, G., Blum, W., Kefauver, C., Awan, F., Smith, L. L., Lapalombella, R., May, S. E., Raymond, C. A., Wang, D.-S., Knight, R. D., Ruppert, A. S., Lehman, A., Ja

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 1.87 MB

english, 2008

11

Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia

Hing, Z. A., Mantel, R., Beckwith, K. A., Guinn, D., Williams, E., Smith, L. L., Williams, K., Johnson, A. J., Lehman, A. M., Byrd, J. C., Woyach, J. A., Lapalombella, R.

Journal:

Year:

2015

Language:

english

File:

PDF, 110 KB

english, 2015

12

FTY720 Shows Promising In vitro and In vivo Preclinical Activity by Downmodulating Cyclin D1 and Phospho-Akt in Mantle Cell Lymphoma

Liu, Q., Alinari, L., Chen, C.-S., Yan, F., Dalton, J. T., Lapalombella, R., Zhang, X., Mani, R., Lin, T., Byrd, J. C., Baiocchi, R. A., Muthusamy, N.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 830 KB

english, 2010

13

Partial persistence of exercise-induced myocardial angiogenesis following 4-week detraining in the rat

Marina Marini, Elisabetta Falcieri, Vittoria Margonato, Davide Treré, Rosa Lapalombella, Simona di Tullio, Cosetta Marchionni, Sabrina Burattini, Michele Samaja, Fabio Esposito, Arsenio Veicsteinas

Journal:

Histochemistry and Cell Biology

Year:

2008

Language:

english

File:

PDF, 552 KB

english, 2008

14

Gene expression profile of rat left ventricles reveals persisting changes following chronic mild exercise protocol: implications for cardioprotection

Betti Giusti, Marina Marini, Luciana Rossi, Ilaria Lapini, Alberto Magi, Andrea Capalbo, Rosa Lapalombella, Simona di Tullio, Michele Samaja, Fabio Esposito, Vittoria Margonato, Maria Boddi, Rosanna A

Journal:

Year:

2009

Language:

english

File:

PDF, 608 KB

english, 2009

15

Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia

Brinton, Lindsey T., Sher, Steven, Williams, Katie, Canfield, Daniel, Orwick, Shelley, Wasmuth, Ronni, Cempre, Casey, Skinner, Jordan, Lehman, Amy, Blachly, James S., Byrd, John C., Lapalombella, Rosa

Journal:

Year:

2020

File:

PDF, 6.68 MB

2020

16

Large-Scale Drug Screen Identifies FDA-Approved Drugs for Repurposing in Sickle-Cell Disease

Cannon, Matthew, Phillips, Hannah, Smith, Sidney, Williams, Katie, Brinton, Lindsey, Gregory, Charles, Landes, Kristina, Desai, Payal, Byrd, John, Lapalombella, Rosa

Journal:

Journal of Clinical Medicine

Year:

2020

File:

PDF, 3.16 MB

2020

17

Heat shock response by EBV-immortalized B-lymphocytes from centenarians and control subjects: a model to study the relevance of stress response in longevity

Marina Marini, Rosa Lapalombella, Silvia Canaider, Antonio Farina, Daniela Monti, Valentina De Vescovi, Marina Morellini, Dina Bellizzi, Serena Dato, Giovanna De Benedictis, Giuseppe Passarino, Raffae

Journal:

Experimental Gerontology

Year:

2004

Language:

english

File:

PDF, 305 KB

english, 2004

18

Glycovariant anti-CD37 monospecific protein therapeutic exhibits enhanced effector cell-mediated cytotoxicity against chronic and acute B cell malignancies

Rafiq, Sarwish, Siadak, Anthony, Butchar, Jonathan P., Cheney, Carolyn, Lozanski, Gerard, Jacob, Naduparambil K., Lapalombella, Rosa, McGourty, Jackie, Moledor, Meghan, Lowe, Richard, Setter, Ben, Jon

Journal:

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

19

Selinexor for advanced hematologic malignancies

Walker, Janek S., Garzon, Ramiro, Lapalombella, Rosa

Journal:

Leukemia and Lymphoma

Year:

2020

File:

PDF, 1.95 MB

2020

20

Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation

Baumhardt, Jordan M., Walker, Janek S., Lee, Yoonji, Shakya, Binita, Brautigam, Chad A., Lapalombella, Rosa, Grishin, Nick, Chook, Yuh Min, Misteli, Tom

Journal:

Molecular Biology of the Cell

Year:

2020

File:

PDF, 3.53 MB

2020

21

Role and regulation of microRNAs targeting BTK in acute myelogenous leukemia

Rizzotto, Lara, Lai, Tzung-Huei, Bottoni, Arianna, Woyach, Jennifer A., Lapalombella, Rosa, Bloomfield, Clara D., Byrd, John C., Sampath, Deepa

Journal:

Leukemia and Lymphoma

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

22

Mild exercise training, cardioprotection and stress genes profile

Marina Marini, Rosa Lapalombella, Vittoria Margonato, Raffaella Ronchi, Michele Samaja, Cristina Scapin, Luisa Gorza, Tullia Maraldi, Paolo Carinci, Carlo Ventura, Arsenio Veicsteinas

Journal:

European Journal of Applied Physiology

Year:

2007

Language:

english

File:

PDF, 374 KB

english, 2007

23

Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia

Lapalombella, R., Sun, Q., Williams, K., Tangeman, L., Jha, S., Zhong, Y., Goettl, V., Mahoney, E., Berglund, C., Gupta, S., Farmer, A., Mani, R., Johnson, A. J., Lucas, D., Mo, X., Daelemans, D., San

Journal:

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

24

Choosy Wolves? Heterozygote Advantage But No Evidence of MHC-Based Disassortative Mating

Galaverni, Marco, Caniglia, Romolo, Milanesi, Pietro, Lapalombella, Silvana, Fabbri, Elena, Randi, Ettore

Journal:

Journal of Heredity

Year:

2015

Language:

english

File:

PDF, 965 KB

english, 2015

25

Sequential events of apoptosis involving docetaxel, a microtubule-interfering agent: A cytometric study

Francesco Fabbri, Silvia Carloni, Giovanni Brigliadori, Wainer Zoli, Rosa Lapalombella, Marina Marini

Journal:

BMC Cell Biology

Year:

2006

Language:

english

File:

PDF, 1.24 MB

english, 2006

26

Thalidomide and lenalidomide as new therapeutics for the treatment of chronic lymphocytic leukemia

Awan, Farrukh T., Johnson, Amy J., Lapalombella, Rosa, Hu, Weihong, Lucas, Margaret, Fischer, Beth, Byrd, John C.

Journal:

Leukemia and Lymphoma

Year:

2010

Language:

english

File:

PDF, 224 KB

english, 2010

27

Modulation of paraoxonase 1 and 3 expression after moderate exercise training in the rat

Romani, R., De Medio, G. E., di Tullio, S., Lapalombella, R., Pirisinu, I., Margonato, V., Veicsteinas, A., Marini, M., Rosi, G.

Journal:

The Journal of Lipid Research

Year:

2009

Language:

english

File:

PDF, 1017 KB

english, 2009

28

Novel SF3B1 in-frame deletions result in aberrant RNA splicing in CLL patients

Agrawal, Anant A., Seiler, Michael, Brinton, Lindsey T., Mantel, Rose, Lapalombella, Rosa, Woyach, Jennifer A., Johnson, Amy J., Zhu, Ping, Warmuth, Markus, Yu, Lihua, Byrd, John C., Smith, Peter G.,

Journal:

Year:

2017

File:

PDF, 1.60 MB

2017

29

Tetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals

Rosa Lapalombella, Yuh-Ying Yeh, Liwen Wang, Asha Ramanunni, Sarwish Rafiq, Shruti Jha, Justin Staubli, David M. Lucas, Rajeswaran Mani, Sarah E.M. Herman, Amy J. Johnson, Arletta Lozanski, Leslie And

Journal:

Year:

2012

Language:

english

File:

PDF, 1.62 MB

english, 2012

30

A Novel Raji-Burkitt's Lymphoma Model for Preclinical and Mechanistic Evaluation of CD52-Targeted Immunotherapeutic Agents

Lapalombella, R., Zhao, X., Triantafillou, G., Yu, B., Jin, Y., Lozanski, G., Cheney, C., Heerema, N., Jarjoura, D., Lehman, A., Lee, L. J., Marcucci, G., Lee, R. J., Caligiuri, M. A., Muthusamy, N.,

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 667 KB

english, 2008

31

Persistence of regenerative myogenesis in spite of down-regulation of activity-dependent genes in long-term denervated rat muscle

Lapalombella, Rosa, Kern, Helmut, Adami, Nicoletta, Biral, Donatella, Zampieri, Sandra, Scordari, Alessandra, di Tullio, Simona, Marini, Marina

Journal:

Neurological Research

Year:

2008

Language:

english

File:

PDF, 506 KB

english, 2008

32

Alemtuzumab (Campath-1H) in the treatment of chronic lymphocytic leukemia

Alinari, L, Lapalombella, R, Andritsos, L, Baiocchi, R A, Lin, T S, Byrd, J C

Journal:

Year:

2007

Language:

english

File:

PDF, 146 KB

english, 2007

33

Targeting BTK through microRNA in chronic lymphocytic leukemia

Bottoni, A., Rizzotto, L., Lai, T.-H., Liu, C., Smith, L. L., Mantel, R., Reiff, S., El-Gamal, D., Larkin, K., Johnson, A. J., Lapalombella, R., Lehman, A., Plunkett, W., Byrd, J. C., Blachly, J. S.,

Journal:

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

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